By the end of the training period trainees will, in respect of the scientific and technical management of an H&I laboratory service and its clinical interface in support of disease diagnosis and pharmacogenetics, be able to prioritise tasks and work independently and be able to:
- analyse, synthesise, evaluate and apply knowledge
- perform, adapt and master a range of technical and clinical skills and procedures
- demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.
Knowledge and understanding
By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to the:
- diseases associated with HLA and other MHC genes, and the emerging knowledge of disease associations
- pharmacogenetic associations with HLA and other MHC genes and the emerging knowledge of pharmacogenetics
- relevance of HLA and other MHC genes in disease
- appropriate H&I tests required for the investigation of pharmacogenetic, HLA and other MHC disease associations
- aetiology and mechanisms of HLA and other MHC disease associations
- role of the H&I laboratory in the investigation of HLA and other MHC disease associations
- role of the H&I laboratory in the investigation of pharmacogenetic associations with HLA and other MHC genes.
Technical and clinical skills
By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of the following technical procedures and laboratory skills:
- select and perform the appropriate range of H&I tests necessary for pharmacogenetic and disease associations
- report results and provide relevant clinical commentary where necessary.
By the end of the training period the trainee will be able to apply knowledge of an H&I laboratory service and its clinical interface in support of disease diagnosis and pharmacogenetic to perform the clinical skills necessary to manage under supervision to:
- advise the clinical team with regard to the relative risks associated with the patient’s HLA or other MHC genes and their disease and/or treatment.
- prioritise workload according to the clinical need of the patients.
Attitudes and behaviours
This module has no attitude and behaviours information.