Title Pure Immunology
Type Stage One
Code HLS043
Requirement Compulsory

Module objective

By the end of the training period trainees will, in respect of developing an in depth knowledge and understanding of immunology related to transplantation in the organisation, assessment and interpretation of data in H&I, be able to

  • analyse, synthesise, evaluate and apply knowledge
  • perform a range of technical and clinical skills and procedures
  • demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to the:

  • role of the receptors, ligands, antigens and genes involved in transplant immunology
  • role of cytokines in transplant immunology
  • structure, function, genetics, generation and significance of immunoglobulin’s
  • structure, function, genetics and significance of the T-cell receptor
  • mechanisms and role of the inflammatory response in solid organ transplant and HSCT
  • concepts of tolerance in transplantation
  • mechanisms of allo-recognition in transplantation
  • role of non-immune mechanisms in transplant failure.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of the following technical procedures and laboratory skills:

  • assess a range of immunological test results in relation to findings in the H&I laboratory.

Attitudes and behaviours

This module has no attitude and behaviours information.


Code Title Action
HLS1-4-20 Histocompatibility & Immunogenetics [v1] View