Title Myeloma and plasma cell disorders
Type Stage Two
Code HLS166
Requirement Compulsory

Module objective

By the end of the training period trainees will, in respect of myeloma and plasma cell disorders, be able to:

  • analyse, synthesise, evaluate and apply knowledge
  • perform, adapt and master a range of technical and clinical skills and procedures
  • demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to

  • the pathogenesis of multiple myeloma
  • other plasma cell disorders including monoclonal gammopathy of uncertain significance, Waldenstrom’s macroglobulinaemia, solitary plasmacytoma, plasma-cell leukaemia and POEMS syndrome
  • laboratory and clinical phenotypic diagnosis and classification
  • bone marrow morphology and cell surface marker analysis
  • cytogenetics and molecular genetics for clonal analysis and prognosis
  • bone disease and hypercalcaemia, hyperviscosity and amyloidosis
  • clinical aspects: clinical history, diagnosis including imaging techniques, treatment strategies including use of radiotherapy.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:

  • have knowledge of pathogenesis, genetics and clinical and laboratory aspects of rarer bleeding disorders
  • advise clinical and laboratory colleagues on the investigation of plasma cell disorders
  • be able to produce a fully interpretative clinical diagnostic laboratory report
  • understand clinical management of plasma cell disorders.

Attitudes and behaviours

This module has no attitude and behaviours information.


Code Title Action
HLS1-2-2-20 Haematology (Haemato-Oncology) [v1] View