|Title||Molecular diagnostics -Haemostasis and thrombosis|
By the end of the training period trainees will, in respect of molecular diagnostics, be able to:
- analyse, synthesise, evaluate and apply knowledge
- perform, adapt and master a range of technical and clinical skills and procedures
- demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.
Knowledge and understanding
By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to
- DNA structure and gene expression, organisation of the human genome, inheritance, mutation mechanisms
- the methodology, principles and practice, assay design, trouble-shooting: PCR, linkage analysis, mutation screening, DNA sequencing
- the genetics of disorders of haemostasis and thrombosis and the role, application and clinical interpretation of genetic diagnosis, family studies/prenatal diagnosis and genetic counselling: haemophilia A, haemophilia B, von Willebrand disease, factor XI deficiency and ‘rarer bleeding disorders’, inherited platelet disorders, thrombophilia (FV Leiden, prothrombin G20210A, AT/PC/PS deficiencies).
Technical and clinical skills
By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:
- core knowledge and understanding of human molecular genetics
- knowledge of technical and practical aspects of molecular biology methods for the investigation of haemostasis and thrombosis
- appropriate use of molecular biology investigations to establish genetic diagnosis and to produce a fully interpretative clinical diagnostic laboratory report
Attitudes and behaviours
This module has no attitude and behaviours information.