Title Exotic and dangerous virus infections
Type Stage Two
Code HLS283
Requirement Optional

Module objective

By the end of the training period trainees will, in respect of understanding the range of infections classified as requiring CL4 laboratory containment and their distribution, differential diagnosis, management and treatment and the importance of rabies and other lyssaviruses as human pathogens, be able to:

  • analyse, synthesise, evaluate and apply knowledge
  • perform, adapt and master a range of technical and clinical skills and procedures and
  • demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

  • the legislative framework underpinning Health and Safety at Work including:
    • Health and Safety At Work Act (1974)
    • RIDDOR
    • COSHH
    • Genetically Modified Organisms (Contained Use) Regulations (2001)
    • Management of Health and Safety At Work Regulations (1999)
    • Viral Haemorrhagic Fever Memorandum (1990)
    • Smallpox Plan (2003)
    • ACDP organism classification
  • viral haemorrhagic fevers, the agents and the management of the ill patient
    • smallpox, the virus and the disease, including an understanding of its potential as a bioterrorism agent
    • rabies and related lyssaviruses, including:
      • virology
      • disease
      • epidemiological trends
      • control
  • CL4 laboratory design and practices.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:

  • perform a risk assessment when required for all procedures undertaken in the laboratory.
  • knowledge of regulations for transportation of patients with Category 4 infections.

By the end of the training period the trainee will be able to apply knowledge of exotic and dangerous virus infections to perform, adapt and master the clinical skills necessary to manage to describe:

  • clinical, virological and epidemiological features and how they affect
  • differential diagnosis and risk assessment of
  • appropriate prophylactic regimens
  • relevant content of ‘Memorandum on rabies: Prevention and control’ DH 2000
  • cabinet and suited CL4 laboratory design, safety features.
  • Trexler isolator, constraints, international alternatives.

Attitudes and behaviours

This module has no attitude and behaviours information.


Code Title Action
HLS2-3-20 Virology [v1] View