Training activity information

Details

Select, perform and interpret serology tests for common viral investigations, including the following and suggest options for management:

  • Blood borne viruses
  • Hepatitis screening
  • Antenatal screens
  • Rashes in pregnancy

Type

Developmental training activity (DTA)

Evidence requirements

Evidence the activity has been undertaken by the trainee​.

Reflection on the activity at one or more time points after the event including learning from the activity and/or areas of the trainees practice for development.

An action plan to implement learning and/or to address skills or knowledge gaps identified.

Reflective practice guidance

The guidance below is provided to support reflection at different time points, providing you with questions to aid you to reflect for this training activity. They are provided for guidance and should not be considered as a mandatory checklist. Trainees should not be expected to provide answers to each of the guidance questions listed.

Before action

  • How does serology contribute to the diagnosis of viral infections, including bloodborne viruses, hepatitis screening, antenatal screens, and rashes in pregnancy?
    • What is your understanding of the principles behind different serological assays?
    • What do you know about the common viral targets in bloodborne virus, hepatitis, antenatal, and pregnancy rash screening?
  • What specific skills in interpreting different serological markers (e.g., antibodies, antigens) will you develop?
    • How will you learn about the diagnostic windows and limitations of serological testing for these viruses?
    • What insights do you expect to gain regarding the clinical significance of different serological profiles and their implications for management?
  • How will you prepare for this DTA?
    • Will you review the principles of ELISA, agglutination, and other serological techniques used in the lab?
    • Will you discuss with your training officer the interpretation algorithms for different viral serology panels?
    • What challenges might arise in interpreting equivocal or discordant serological results?
    • How will you consider the impact of factors like immunocompromise on serological responses?
    • How do you feel about learning to interpret serological tests which often require careful consideration of the clinical context?

In action

  • What specific viral serology tests are you currently performing or interpreting (e.g., ELISA for HIV antibodies, Hepatitis B surface antigen, Rubella IgG, Parvovirus B19 IgM)?
    • How are you approaching the execution or interpretation of these assays? Why are you doing it this way (e.g., following specific kit instructions, understanding the clinical significance of different antibody types)?
    • What decisions are you making regarding the interpretation of borderline or equivocal results?
    • What aspects of performing or interpreting these tests feel intuitive to you, and what requires more conscious effort (e.g., understanding window periods, interpreting complex serological profiles)?
  • How effective are your current actions in obtaining or interpreting accurate and clinically relevant serological results?
    • What challenges are you facing during the process (e.g., understanding the limitations of serology, dealing with false positives or negatives)?
    • What can you learn about viral serology and its role in diagnosis and screening as the activity unfolds?
    • How does this activity connect to your understanding of virology, maternal health, and public health screening programmes?
  • Are there alternative approaches you could be considering if results are inconclusive or unexpected (e.g., repeating tests, using alternative serological assays, considering molecular testing)?
    • What support or guidance might you need in this moment from a senior colleague or the training officer regarding the interpretation of complex serological results?
    • Are you working within your scope of practice when selecting, performing, and interpreting these tests and considering management options?

On action

  • Begin by summarising the key points of the experience working with viral serology.
    • What were the most significant observations regarding the serological techniques used or the interpretation of results for specific conditions like blood-borne viruses, hepatitis, antenatal screens, or rashes in pregnancy?
  • What skills or knowledge did you develop or improve through this DTA, specifically in selecting appropriate serological tests, performing them correctly, interpreting complex serological profiles, or contributing to management based on these results?
    • Were there any unexpected challenges (e.g., equivocal results, understanding seroconversion kinetics) or successes? What did you learn from these?
    • In what ways did your ‘reflection-in-action’ influence your approach during the activity, such as considering repeat testing or seeking expert advice?
  • What areas for continued development have been identified, perhaps concerning the interpretation of specific serological markers or understanding the clinical context influencing results?
    • How can you apply the learning from this activity to your routine practice when handling and reporting viral serology?
    • Identify the specific actions or ‘next steps’ you will take to consolidate this learning.
    • What support or resources might you need to further develop in these areas?

Beyond action

  • Revisit your initial reflect-on-action notes for this DTA. What additional insights have you gained since the initial reflection?
    • Has discussing complex serology profiles or antenatal screening results with colleagues or clinicians altered your perspective?
    • How did this specific viral serology experience compare to other types of serological testing or molecular viral testing?
    • What patterns or recurring challenges (e.g., interpreting equivocal results, understanding timing of seroconversion) have you identified across multiple serology samples?
    • Have you discussed viral serology interpretation or screening programmes during professional storytelling with peers or senior colleagues?
    • What new perspectives did this bring, especially regarding clinical implications or public health follow-up?
  • How have the skills (e.g., understanding different assay formats, interpreting complex antibody/antigen patterns, linking serology results to clinical context) you developed during this DTA influenced your approach to serological testing for other pathogens?
    • Have you applied the learning from this DTA, such as appreciating the importance of patient history or the implications of screening results, to other aspects of your microbiology practice?
    • How does the learning from this DTA contribute to your preparedness for observed assessments like interpreting syphilis serology or communicating results?
  • What transferable skills in understanding assay principles, interpreting multi-parameter results, and appreciating the role of screening in public health, developed through this DTA, will be valuable throughout your training and beyond?
    • Identify clear actions for continued development related to viral serology, screening programmes, or liaison with clinical teams based on your cumulative experiences and reflections.

Relevant learning outcomes

# Outcome
# 1 Outcome

Select and perform tests to investigate common infections from a range of sample types following guidance and fulfilling health and safety requirements

# 2 Outcome

Interpret the results of tests used to investigate common infections from a range of sample types with consideration of laboratory quality assurance and quality control

# 3 Outcome

Identify options for management of common infections based on test results and clinical context, considering infection control, guidelines and public health requirements

# 4 Outcome

Perform and interpret molecular techniques for the investigation of common infections following guidance and fulfilling health and safety requirements