Training activity information
Details
Interpret and report gene fusion testing, to include:
- FISH, e.g. lung cancer
- RT-PCR, e.g AML, ALL
- RNA fusion panel, e.g. NTRK
Type
Developmental training activity (DTA)
Evidence requirements
Evidence the activity has been undertaken by the trainee​.
Reflection on the activity at one or more time points after the event including learning from the activity and/or areas of the trainees practice for development.
An action plan to implement learning and/or to address skills or knowledge gaps identified.
Considerations
- Interpretation of results, including diagnostic and treatment recommendations, taking into account the relationships between genetic markers, other testing modalities and clinical diagnosis
- Evidence base, literature and online databases
- The role of large scale national and international projects and trials focused on acquired disease
- Integrated reporting
- Local format for reporting
- Best practice guidance
- Local and national guidance
- Implications and recommendations
- Sensitivity and limitations
- Quality control, including IQC, and EQA
- Nomenclature, correct scientific and clinical terminology (ISCN and HGVS)
- Local SOPs
- Confidentiality and information governance
- Communication of complex scientific information to clinicians and patients
- Limitations of the method
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 3 |
Outcome
Analyse, interpret and report tests for patients referred with sporadic cancer. |
| # 7 |
Outcome
Analyse, interpret and report gene fusion testing in cancer referrals. |