Training activity information
Details
Select the correct genetic tests for patients referred with germline cancer susceptibility, to include:
- Breast/ovarian
- Lynch syndrome
- FAP
Type
Entrustable training activity (ETA)
Evidence requirements
Evidence the activity has been undertaken by the trainee repeatedly, consistently, and effectively over time, in a range of situations. This may include occasions where the trainee has not successfully achieved the outcome of the activity themselves. For example, because it was not appropriate to undertake the task in the circumstances or the trainees recognised their own limitations and sought help or advice to ensure the activity reached an appropriate conclusion.
Reflection at multiple timepoints on the trainee learning journey for this activity.
Considerations
- Identification of individuals at an increased risk of cancer development, including family history, and scoring systems
- Interface between germline and acquired genetic testing – e.g. ‘mainstreaming’ of BRCA1/2 testing, IHC testing for defective mismatch repair in CRC
- Principals of indirect testing and implications for the patient
- Presymptomatic testing
- Sample types/tubes
- Testing pathways
- Local SOPs
- Health and safety
- Consent process for minors
- Onward referrals
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 |
Outcome
Apply appropriate sample selection criteria for the commonly referred cancer samples, taking into account the implications of the referral with respect to sample type, sampling mixed cell populations, limits of detection, sensitivity of assay and patient management. |
| # 2 |
Outcome
Select the laboratory testing strategy for the commonly referred cancer samples at all stages of the patient pathway. |