Training activity information
Details
Select the correct genetic tests for gene fusion testing on oncology samples to include;
- FISH, e.g. lung cancer
- RT-PCR, e.g. AML, ALL
- RNA fusion panel, e.g. NTRK
Type
Developmental training activity (DTA)
Evidence requirements
Evidence the activity has been undertaken by the trainee​.
Reflection on the activity at one or more time points after the event including learning from the activity and/or areas of the trainees practice for development.
An action plan to implement learning and/or to address skills or knowledge gaps identified.
Considerations
- Role of fusion testing in cancer patients for diagnosis, prognosis, treatment options, minimal residual disease, monitoring and patient management
- Sample acceptance criteria
- Sample transport and storage
- Reason for referral
- Sample types/tubes
- Testing pathways
- Local SOPs
- Health and safety
- Consent process for minors
- Onward referrals
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 |
Outcome
Apply appropriate sample selection criteria for the commonly referred cancer samples, taking into account the implications of the referral with respect to sample type, sampling mixed cell populations, limits of detection, sensitivity of assay and patient management. |
| # 2 |
Outcome
Select the laboratory testing strategy for the commonly referred cancer samples at all stages of the patient pathway. |