Training activity information

Details

Perform immunohistochemical staining to demonstrate various antigens in relation to the assessment of:

  • Non-malignant disease
  • Pre-malignant disease
  • Malignant disease

Type

Entrustable training activity (ETA)

Evidence requirements

Evidence the activity has been undertaken by the trainee repeatedly, consistently, and effectively over time, in a range of situations. This may include occasions where the trainee has not successfully achieved the outcome of the activity themselves. For example, because it was not appropriate to undertake the task in the circumstances or the trainees recognised their own limitations and sought help or advice to ensure the activity reached an appropriate conclusion. ​

Reflection at multiple timepoints on the trainee learning journey for this activity.

Considerations

  • Internal quality control of antibody staining, including IHC positive control material and staining patterns of antibodies in tissues and tumours
  • Impact of specialist pre and post analytical factors
  • Antigen retrieval
  • Clinical appropriateness and implications of testing
  • Local SOPs
  • National and local policies and guidelines
  • RCPath tissue pathways
  • RCPath cancer datasets
  • Screening programme guidance
  • NICE guidance
  • Troubleshooting
  • Tumour panels

Relevant learning outcomes

# Outcome
# 3 Outcome

Employ IHC to identify various antigens and molecular markers.

# 4 Outcome

Practice safely in accordance with quality management and accreditation standards.