Training activity information


Perform a donor search  for a patient with no ‘HLA-matched’ donors and select potential alternative related or unrelated donors for HSCT


Entrustable training activity (ETA)

Evidence requirements

Evidence the activity has been undertaken by the trainee repeatedly, consistently, and effectively over time, in a range of situations. This may include occasions where the trainee has not successfully achieved the outcome of the activity themselves. For example, because it was not appropriate to undertake the task in the circumstances or the trainees recognised their own limitations and sought help or advice to ensure the activity reached an appropriate conclusion. ​

Reflection at multiple timepoints on the trainee learning journey for this activity.


  • Local and national procedures
  • Role of donor registries in the search process
  • Types of HSCT donor
  • Factors affecting alternative HSCT donor selection
  • National and international standards and legislation relating to HSCT
  • Relevant advisory groups for donor selection
  • Sources of stem cells
  • Local protocols for the clinical and laboratory work up of patients awaiting HSCT
  • Malignant and non-malignant conditions treated by HSCT
  • Impact of blood product support through conditioning and impact on HLA antibody formation/need to screen for antibodies to aid donor selection (and timing of screening tests)

Relevant learning outcomes

# Outcome
# 1 Outcome

Apply the appropriate strategy for the investigation of patients being considered for haematopoietic stem cell transplantation (HSCT), interpret and report results of the investigation in the correct clinical context.

# 2 Outcome

Assess the suitability of potential related and unrelated matched and mismatched donors for HSCT.

# 4 Outcome

Practice effectively in partnership with other clinical specialisms and the wider multidisciplinary team in the investigation of HSCT to deliver safe and effective patient care.