Competency information

Details

Determine the type I and type II error that is acceptable.

Considerations

  • Formulation of the null hypothesis.
  • Statistical hypothesis testing.
  • Type I (false positive) and type II (false negative) errors.
  • Primary and secondary outcomes.
  • Statistical vs clinical significance.
  • Expected magnitude of effect.
  • Necessary assumptions, e.g. proportion of controls exposed, standard deviation of the outcome measurement.
  • How power may have affected the interpretation of the study results.

Relevant learning outcomes

# Outcome
# 3 Outcome Calculate the sample size required for an analytical study, or the power of a study that has already been conducted, and discuss the impact of this on the study and the interpretation of findings in relation to patients or the public.