Competency information

Details

Perform laboratory methods for HLA antibody detection for example:

  • Complement dependent cytotoxicity
  • ELISA
  • Flow cytometry
  • X-MAP Technologies(Luminex)

Considerations

  • Principles of HLA antibody production.
  • Sources of HLA sensitisation.
  • Selection and principles of laboratory methods for HLA antibody detection and definition.
  • Internal quality controls and external quality assessment measures appropriate to the methods used.
  • Correct and safe use of equipment used.
  • How to assure the quality of personal practice.

Relevant learning outcomes

# Outcome
# 1 Outcome Select and perform laboratory tests for Human Leukocyte Antigen (HLA) antibody identification, definition and data analysis.
# 2 Outcome Select and perform laboratory tests required for the clinical work up of patients awaiting solid organ transplantation, including cross matching for solid organ transplantation.
# 3 Outcome Perform the clinical and laboratory work up of patients referred for investigation of platelet refractoriness.
# 5 Outcome Apply specific accreditation standards governing the use of serological practices.