Competency information

Details

Select appropriate sera for the cross-matching of donor and recipients in accordance with local and national guidelines.

Considerations

  • How to assure the quality of personal practice.
  • Principles of laboratory methods for crossmatching donors and recipients for solid organ transplantation
    • Complement dependent cytotoxicity
    • Flow cytometry
  • Internal quality controls and external quality assessment measures appropriate to the methods used.
  • Problems likely to be encountered in these assays, including
  • cellular/microbiological contamination
  • false negative and positive reactions
  • low/high cell yield
  • poor viability of cells
  • drug interactions

Relevant learning outcomes

# Outcome
# 2 Outcome Select and perform laboratory tests required for the clinical work up of patients awaiting solid organ transplantation, including cross matching for solid organ transplantation.
# 5 Outcome Apply specific accreditation standards governing the use of serological practices.