Competency information
Details
Lifestyle factors and exposures which pose heritable risk.
Considerations
- Chemotherapy and radiotherapy, associated mutagenic and teratogenic risks and guidance for patients.
- The effects of age, diet and obesity on the sperm genome.
- Assess the evidence around the effects of
- Smoking
- Alcohol
- Illegal drug use (e.g. cannabinoids)
- Performance enhancing drugs (i.e. steroids)
- Emerging evidence, including from animal data, around paternally-heritable epigenetic effects.
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 | Outcome Gather a clinical history for a patient, including relevant genetic and heritable risks. |
| # 2 | Outcome Gather a history from a potential sperm donor. |
| # 3 | Outcome Evaluate the risk of affecting offspring for different heritable conditions exercising their own professional judgement. |
| # 4 | Outcome Review a set of notes to link the cause of infertility with a genetic factor and produce an interpretive report of the investigations with a suggested treatment plan. |