Competency information
Details
Observe and assist with the preparation of samples for genetic testing.
Considerations
- The purpose, process, capabilities and limitations of cell culture procedures and associated equipment.
- Cell culture, slide making and chromosome preparation techniques (G-banding) and their importance in the investigation process.
- The purpose, process, capabilities and limitations of nucleic acid extraction procedures and associated equipment.
- Relevant protocols and their application, including health and safety considerations.
- Requirements for containment levels to maintain the integrity of the sample and to protect the member of staff.
- The quality and quantity of DNA/RNA required for each test to be performed.
- Factors affecting the quality of extractions.
- The range and requirements for records and documentation associated with extractions.
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 | Outcome Observe and reflect on the patient pathway from sample receipt to issuing of the clinical reports for a range of genetic referrals. |
| # 2 | Outcome Observe and reflect on preparation of samples for genetic analysis in current use. |
| # 3 | Outcome Apply the correct genetic nomenclature to genetic alterations, including International System for Chromosome Nomenclature (ISCN) and Human Genome Variation Society (HGVS) nomenclature. |
| # 4 | Outcome Identify the appropriate testing strategy for a range of referral reasons. |