Competency information
Details
Perform the analysis and interpretation of rapid aneuploidy screening results.
Considerations
- The technical pathway for rapid aneuploidy screening including its limitations, sensitivities, essential requirements for good laboratory practice and the risks.
- How to identify potential for error, how this is mitigated and its potential effects.
- Best practice guidelines compared with laboratory practice and any differences between the two.
- Confined placental mosaicism (CPM), its origins and effects for both the fetus and the test.
- Fetal mosaicism, its origins and effects for both the fetus and the test.
- Further technical testing which may be required.
- Reporting strategies.
- Maternal cell contamination (MCC).
- How to identify, quantify and qualify MCC.
- Reporting
- Polysomy, its origins and effects for both the fetus and the
- The considerations required for twin and other multiple pregnancies.
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 | Outcome Apply an appropriate testing strategy (the right sample, the right test, for the right reasons) meeting all relevant KPIs (key performance indicators, however defined). |
| # 2 | Outcome Analyse and interpret results of specific defined tests. |
| # 3 | Outcome Identify and respond appropriately to results. |
| # 5 | Outcome Act in accordance with the high level of laboratory risk associated with prenatal testing and within limits of their responsibilities. |