Competency information

Details

 Assist with the preparation of samples for analysis, selecting the correct sample processing pathway(s) :

  • CML
  • CLL
  • Ph-negative myeloproliferative malignancies
  • Burkitt lymphoma

Considerations

  • Health and safety requirements for processing of fresh peripheral blood or bone marrow samples and cell culture
  • Cell culture and preparation of G-banded chromosomes
  • Factors affecting quality of samples for G- banding of leukaemia samples
  • Preparation of slides for analysis from paraffin embedded blocks
  • Selection of the appropriate area for analysis (eg morphological assessment of H&E stained slide)
  • Principles of relevant technologies Health and safety requirements for use of appropriate equipment (eg fluorescence microscope)
  • Chromosomal changes in the relevant disorders Role of molecular cytogenetics for diagnosis and prognosis
  • Application of molecular cytogenetic analysis to guide treatment choice

Relevant learning outcomes

# Outcome
# 2 Outcome Interact with relevant disciplines for the diagnosis and treatment of haematological malignancies