Competency information
Details
Analyse and interpret genetic analysis for suspected chronic myeloid leukaemia
Considerations
- Health and safety requirements for processing of fresh peripheral blood or bone marrow samples
- Principles of molecular genetic approaches for identification of BCR-ABL1 fusion oncogene
- Factors affecting quality of samples for successful analysis
- Limitations of the procedure
- Consideration of rare and unusual transcript types
- Internal quality control for assays Importance of external quality assurance
- Role of validation and verification of procedures and equipment
- Understanding of assay accreditation and ISO 15189 or equivalentNational guidelines for pathways and procedures
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 3 | Outcome Apply the appropriate testing strategy that would lead to the diagnosis of a range haematological malignancies |
| # 4 | Outcome Implement the use of appropriate assays for the diagnoses and monitoring of a range of haematological malignancies |