Competency information
Details
Receive samples and decide on the appropriate diagnostic pathway for patients with a suspected diagnosis of the following conditions :
- AML
- MDS
- CLL
- Large B cell lymphoma
Considerations
- WHO classification of the relevant disorders
- Usual clinical features of the relevant disorders
- Morphological features of the peripheral blood
- film,bone marrow aspirate, bone marrow trephine or lymph node biopsy (as appropriate) for the relevant disorders
- Immunophenotypic features, where relevant, of the disorders
- Interaction between different laboratory and clinical approaches for diagnosis
- National and international guidelines for laboratory diagnosis of haematological malignancies
- Identification of samples and documentation
- Factors affecting sample quality and suitability for examinations
- Appropriate choice of assays according to clinical details and results of other laboratory findings
- Application of cytogenetic analysis to guide treatment choice
- Significance of array CGH (SNP array) Storage of samples
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 | Outcome Interact with relevant disciplines and apply appropriate approaches for the diagnosis and treatment of heterogeneous myeloid and lymphoid malignancies |
| # 2 | Outcome Recognise the main clinical features and morphological characteristics of AML, MDS, CLL and large B cell lymphomas |
| # 3 | Outcome Apply the appropriate testing strategy for a range of complex myeloid malignancies including AML, MDS, considering the approach for subclassification and prognosis of disease |