Competency information

Details

Analyse and interpret appropriate genetic investigations for the monitoring of patients (eg AML)

Considerations

  • Requirements of the sample for successful monitoring of residual disease
  • Health and safety requirements for processing fresh samples
  • Principles of the techniques for monitoring residual disease
  • Choice of appropriate monitoring approaches for different patients
  • Limitations of each procedure including limit of detection, sensitivity and specificity
  • Factors affecting quality of molecular results Interpretation of results
  • National and international guidelines for monitoring of residual disease
  • Clinical and therapy relevance of monitoring results

Relevant learning outcomes

# Outcome
# 3 Outcome Apply the appropriate testing strategy for a range of complex myeloid malignancies including AML, MDS, considering the approach for subclassification and prognosis of disease
# 4 Outcome Implement the appropriate strategy for monitoring residual disease in patients with acute myeloid leukaemia