Competency information
Details
Perform and interpret appropriate genetic investigations for the monitoring of patients after bone marrow transplantation
Considerations
- Principles of the techniques for post transplant chimerism analysis
- Requirements of the sample for successful chimerism analysis
- Limitations of the procedure including limit of detection, sensitivity and specificity
- Factors affecting quality of molecular results Interpretation of results
- Clinical implications of the results obtained
- National and international guidelines for post transplant chimerism analysis
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 3 | Outcome Apply the appropriate testing strategy for a range of complex myeloid malignancies including AML, MDS, considering the approach for subclassification and prognosis of disease |
| # 6 | Outcome Appreciate the role of stem cell transplantation and monitor the presence of donor material by ‘chimerism analysis’ |