Competency information
Details
Analyse samples for clinically significant gene fusions
Considerations
- Basic chromosome identification
- Karyotype analysis
- Numerical and structural abnormalities
- Correct ISCN nomenclature
- Chromosomal changes in relevant disorders that are detectable by G-banding
- Principles of relevant technologies g. FISH, RT-PCR, RNA-Seq
- Internal quality control for assays
- Importance of external quality assurance
- Role of validation and verification of procedures and equipment
- Understanding of ISO 15189 or equivalent
- National guidelines for pathways and procedures
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 3 | Outcome Apply the appropriate testing strategy for a range of complex myeloid malignancies including AML, MDS, considering the approach for subclassification and prognosis of disease |
| # 7 | Outcome Interpret and report on the relevant laboratory procedures for the diagnosis of a range of myeloid and lymphoid malignancies |