Thrombophilia

Details

Title

Thrombophilia

Type

Stage One

Module code

HLS028

Requirement

Compulsory

Module objective

By the end of the training period trainees will, in respect of thrombophilia, be able to:

• analyse, synthesise, evaluate and apply knowledge
• perform a range of technical and clinical skills and procedures
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

1. Health and safety legislation and guidance
2. ACDP categorisation of biological agents
3. Laboratory safety and containment
4. Transport regulations

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

• coagulation inhibitors and the fibrinolytic pathway
• epidemiology and molecular basis of thrombophilia
• pathogenesis of thrombosis in arteries, veins and the microcirculation
• risk factors for thrombosis
• natural history, presentation and complications of thrombophilia, including both inherited and acquired disorders
• techniques for the measurement of Protein C, Protein S, AT, APCR and lupus anticoagulant.
• molecular techniques used in diagnosis of heritable thrombophilia

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of the following technical procedures and laboratory skills:

• demonstrate appropriate use of laboratory methods to reach a diagnosis
• interpret and apply laboratory results to assist in patient management
• interpret and apply laboratory results to patient diagnosis and monitoring.