Histocompatibility and Immunogenetics Blood transfusion 1

Details

Title

Histocompatibility and Immunogenetics Blood transfusion 1

Type

Stage One

Module code

HLS038

Requirement

Compulsory

Module objective

By the end of the training period trainees will, in respect to the techniques used in the application of H&I services, obtain a working knowledge of the scientific, clinical and technical aspects of H&I and be able to:

• analyse, synthesise, evaluate and apply knowledge
• perform a range of technical skills and procedures
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to the:

• different types of blood products transfused and the emerging developments in blood transfusion
• immunology theory relating to blood transfusion, HLA and transplant
• relevance of blood transfusion to the development of HLA and non-HLA antibodies
• complications and factors affecting the outcome of blood transfusion
• role of the H&I laboratory in the investigation of complications of blood transfusion and the provision of compatible blood components
• appropriate H&I tests required for the investigation of complications of blood transfusion and the provision of compatible blood components
• organisation and function of the transfusion service and local transfusion laboratory in the provision of blood products and the investigation of transfusion related issues
• process for selection of blood products for transfusion in the presence of HLA and non-HLA antibodies
• legislation, standards and ethical issues relating to blood transfusion.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of the following technical procedures and laboratory skills:

• select and perform the appropriate range of H&I tests necessary for the pre-transfusion workup of patients sensitised to blood products
• select and perform the appropriate range of H&I post transfusion monitoring tests for patients sensitised to blood products
• select and perform the appropriate range of H&I tests necessary for the investigation of transfusion reactions, e.g. TRALI
• report results and provide relevant clinical commentary where necessary.

By the end of the training period the trainee will be able to apply knowledge of an H&I laboratory service and its clinical interface in support of the blood transfusion team to perform the clinical skills necessary to manage under supervision to:

• participate at relevant MDT meetings, acting as a liaison between the laboratory and the transfusion team
• advise the clinical team with regard to the outcome of investigations for transfusion reactionsadvise the clinical team with regard to selection and compatibility of patient and blood products
• prioritise workload according to the clinical need of the patients.