Transfusion Therapy: Selection and Appropriate use of Blood Components and Plasma Derivatives

Details

Title

Transfusion Therapy: Selection and Appropriate use of Blood Components and Plasma Derivatives

Type

Stage One

Module code

HLS056

Requirement

Compulsory

Module objective

By the end of the training period with respect to the selection and appropriate use of blood components and plasma derivatives the trainee will be able to:

• analyse, synthesise, critically evaluate and apply knowledge
• perform a range of technical procedures and demonstrate a range of clinical skills
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

• the composition, characteristics, specification, storage and labelling requirements of blood components available in the UK, their derivations and secondary products including:
  • red cell donations
  • platelet donations (pooled and apheresis)
  • granulocyte donations
  • fresh frozen plasma and cryoprecipitate
  • albumin
  • coagulation factors
  • prophylactic anti-D immunoglobulin
• BSCH guidelines relevant to the administration of blood components and plasma derivatives including:
  • red cells, platelets and granulocytes
  • irradiated blood components
  • fresh frozen plasma and cryoprecipitate
  • anti-D immunoglobulin
• the special transfusion requirements of patient groups considering age, underlying pathology and vulnerability
• the use and availability of specially selected products, including:
  • IgA negative blood products.
  • HPA-1a-,5b- platelets.
  • washed red cells
  • HLA-matched red cells
  • blood components from donors at low risk of vCJD

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of a range of technical procedures and laboratory skills and will be able to:

• select appropriate blood products for the treatment of patients with:
  • major haemorrhage and trauma
  • haematological disorders
  • HLA, HPA or HNA antibodies
  • refractoriness to random donor platelets
  • ITP, NAITP or PTP
  • IgA deficiency with anti-IgA
  • stem cell or solid organ transplant
  • disorders of haemostasis and thrombosis
• critically evaluate the special requirements of obstetric, antenatal, neonatal and young patients
• perform the checks and assurances required for products subjected to secondary processing including washed and irradiated products
• critically evaluate and optimise the management of inventories of locally-held stock in order to meet patient requirements in a timely manner

By the end of the training period with respect to the selection and appropriate use of blood components and plasma derivatives, trainees will be able to:

• provide advice to clinical colleagues on safe transfusion support for individual patients, appraising the relevance and significance of the patient’s condition, and the availability of different blood components and plasma derivatives
• provide advice to clinical colleagues on requirements for secondarily processed blood components