Enzymology

Details

Title

Enzymology

Type

Stage Two

Module code

HLS132

Requirement

Compulsory

Module objective

By the end of the training period trainees will, in respect of competencies in the clinical biochemistry of enzymology, be able to:

• analyse, synthesise, evaluate and apply knowledge
• perform a range of technical and clinical skills and procedures
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

(N.B. Items in italics would probably not be encountered universally)

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

• enzyme stability
• the mechanisms for induction of enzymes
• the structural basis, separation and quantitation of isoenzymes
• the following assays and how they can be used in the investigation, diagnosis, monitoring and management of disease
• the limitations of the following tests:
  • amylase and lipase
  • alkaline phosphatase
  • aminotransferases
  • angiotensin converting enzyme
  • creatine kinase
  • lactate dehydrogenase
  • gamma-glutamyl transferase
  • cholinesterase and variants

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of the following technical procedures and laboratory skills:

• the technical aspects of enzyme analysis
• the results of laboratory enzyme analysis
• perform unsupervised the analysis of alkaline phosphatase isoenzymes or other isoenzymes.

By the end of the training period trainees will, in respect of the competencies in the clinical biochemistry of enzymology, be able to perform the clinical skills necessary to manage under supervision:

• liaison with the clinical team on the appropriate specimen collection, specimen handling, investigation, diagnosis, interpretation and monitoring conditions involving enzyme analysis.