Therapeutics 2

Details

Title

Therapeutics 2

Type

Stage Two

Module code

HLS149

Requirement

Compulsory

Module objective

By the end of the training period trainees will, in respect of the modes of action and appropriate use of immunosuppressive drugs and other therapies appropriate to immunology* be able to:

• analyse, synthesise, evaluate and apply knowledge
• perform, adapt and master a range of technical and clinical skills and procedures and
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

*CyA

MMF

Tacro

Aza

Cyroines and their inhibitors and modulators.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

• appropriate laboratory investigations
• therapeutic interventions:
  • putative mechanisms of action of various immunological therapies
  • principles of the various therapeutic options to guide the most appropriate treatment for an individual patient
• a working knowledge of the evidence base for the use of various immunological therapies
• the appropriate laboratory investigation that should be used to monitor the clinical effectiveness and toxicity of the drug
• immunosuppressive drugs and their toxicities in solid organ and SC transplantation
• the principles of gene therapy for PID.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills

• the interactions between donor selection, H&I tests.

By the end of the training period the trainee will be able to apply knowledge of immunosuppressive drugs and other therapies appropriate to immunology to direct a diagnostic immunology laboratory to perform, adapt and master the clinical skills necessary to manage:

• the principles of their actions to aid clinical decision making
• strategies to diagnose and monitor immunological diseases
• the biological activity and the impact of the drug on the immune system
• be familiar with national guidance on appropriate test selection and use where relevant, e.g. NICE.