Transfusion Support for Organ Transplantation

Details

Title

Transfusion Support for Organ Transplantation

Type

Stage Two

Module code

HLS195

Requirement

Compulsory

Module objective

By the end of the training period with respect to transfusion support for organ transplantation, the trainee will be able to:

• analyse, synthesise, critically evaluate and apply knowledge
• perform, adapt and master a range of technical and clinical skills and procedures
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

• the Red Book and BCSH guidelines on the use of irradiated blood
• the selection of HLA-matched red cells and platelets to avoid pre-transplant
• strategies to overcome ABO incompatibility including:
  • plasma exchange
  • immunosuppression
  • immunoadsorption
  • quantitation of anti-A and anti-B in prospective transplant recipients
• immune haemolysis as result of passenger lymphocyte syndrome and treatment
• ABO group after organ transplantation and effect on transfusion requirements
• the role of CMV
• transfusion support for immunosuppressed patients
• the role of HLA in selection of donors for organ transplantation

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of a range of technical procedures and laboratory skills and will be able to:

• adapt and master transfusion support for organ transplantation
• select, perform and interpret laboratory tests to assess and monitor ABO antibody levels

By the end of the training period with respect to clinical and laboratory transfusion, trainees will be able to perform the clinical skills necessary to:

• provide expert advice on significance of ABO incompatibility and anti-A and anti-B antibody concentrations in ABO incompatible organ transplantation
• provide expert advice on the transfusion support for patients undergoing organ transplantation including the provision of HLA-matched red cells