Antimicrobial chemotherapy

Details

Title

Antimicrobial chemotherapy

Type

Stage One

Module code

HLS210

Requirement

Compulsory

Module objective

By the end of the training period trainees will, in respect of antimicrobial chemotherapy, be able to:

• analyse, synthesise, evaluate and apply knowledge
• perform a range of technical and clinical skills and procedures
• demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice  at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to the:

• range of therapies available for infectious disease and the clinical indications for their use
• importance and range of adverse effects including allergic reactions
• importance and range of side effects
• classification of antimicrobial agents
• mechanism of action of antimicrobial agents
• mechanisms for development of resistance to these agents
• basic principles of prophylaxis, with antimicrobials, vaccines and immune globulins
• monitoring levels of antimicrobial chemotherapy for efficacy and patient safety
• importance of interactions between antimicrobial agents and other therapeutic agents therapeutic use of immune globulins.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance of the following technical procedures and laboratory skills:

• laboratory techniques
  • conventional techniques for susceptibility testing including disc, broth dilution, E-test
  • automated/semi-automated susceptibility testing
  • nucleic acid techniques, including gene sequencing
  • reference laboratory referral where appropriate
  • antimicrobial monitoring assays
  • assessing host factors affecting antimicrobial response
• systems for ensuring the quality assurance of test procedures and reagents
  • use of appropriate internal controls and monitoring assay performance
  • internal quality assurance
  • external quality assurance
• validity and reliability of test results and their application
  • Understanding of uncertainty of measurement
  • Using systems to produce timely, accurate and relevant laboratory reports with appropriate interpretive comments.

By the end of the training period the trainee will be able to apply knowledge of antimicrobial chemotherapy to perform the clinical skills necessary to manage under supervision:

• to apply knowledge of treatment and prevention strategies.