Module: HLS333

Gastrointestinal Stromal Tumours GISTs

Module information

Details

Title
Gastrointestinal Stromal Tumours GISTs
Type
Stage Two
Module code
HLS333
Requirement
Compulsory

Module objective

By the end of the training period trainees will, in respect to a thorough understanding, theoretical and practical, of the knowledge, theoretical skills and clinical skills necessary to be proficient in GIST molecular testing, be able to:

  • analyse, synthesise, evaluate and apply knowledge
  • perform, adapt and master a range of technical and clinical skills and procedures and
  • demonstrate the attitudes and behaviours necessary for professional practise as a Consultant Clinical Scientist dealing with the complexities, uncertainties and tensions of professional practise at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

  • Epidemiology and pathophysiology of disease
  • Laboratory and clinical phenotypic diagnosis and classification
  • Molecular classification of GIST at a mutation, gene amplification and protein expression levels
  • Clinical aspects: therapeutic principles and measures

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following skills:

  • Competency in the laboratory investigation, diagnosis and follow-up of patients with GIST
  • Knowledge to validate, carry out and trouble-shoot tests for c-KIT mutations and PDGFRA mutations
  • Readiness to validate, whenever needed, other single
  • Knowledge to validate, carry out and trouble-shoot multiple biomarker testing, at a DNA or RNA level, whenever relevant.

By the end of the training period the trainee will be able to apply knowledge of the general principles of GIST to perform, adapt and master the clinical skills necessary to manage and to understand the:

  • production a fully interpretative clinical diagnostic laboratory report
  • clinical management of GIST

Attitudes and behaviours

Information:

This module has no attitude and behaviours information.

Module assigned to

Specialties

Specialty code Specialty title Action
Specialty code HLS3-3-20 Specialty title Molecular Pathology of Acquired Disease [V1] Action View