Molecular Pathology for Histopathology

Details

Title

Molecular Pathology for Histopathology

Type

Stage One

Module code

HLS396

Requirement

Compulsory

Module objective

By the end of the training period trainees will, in respect to background and principles, be able to:

• Analyse, synthesise, evaluate and apply knowledge
• Perform a range of technical and clinical skills and procedures
• Demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

Fundamentals of Molecular Biology

• Identifies the origins and consequences of germline variation and somatic mutations, including DNA methylation and gene expression changes

Fundamentals of Genetics

• Identifies the structure of genes including translation and transcription, factors affecting gene expression and inheritance patterns

Molecular Techniques

• Identifies molecular techniques

Molecular Tests

• Describes molecular tests currently performed on histological samples

Technical and clinical skills

Fundamentals of Molecular Biology

• Demonstrates the origins of and justifications for molecular tests

Fundamentals of Genetics

• Recognises the factors affecting transcription and translation

Molecular Techniques

• Demonstrates awareness of principles, practical knowledge of sequencing, PCR, microarrays (DNA and RNA), in situ hybridisation and mutation detection

Molecular Tests

• Interprets the common molecular tests