Training activity information
Details
Select the correct genetic tests for patients referred with acquired solid tumours, to include:
- Ovarian cancer
- Colorectal cancer
Type
Developmental training activity (DTA)
Evidence requirements
Evidence the activity has been undertaken by the trainee.
Reflection on the activity at one or more time points after the event including learning from the activity and/or areas of the trainees practice for development.
An action plan to implement learning and/or to address skills or knowledge gaps identified.
Considerations
- Role of genetic testing in the diagnosis and treatment (clinical utility) of acquired solid tumours, including ‘actionability’
- Sample acceptance criteria
- Sample transport and storage
- Reason for referral – diagnosis, prognosis, treatment and monitoring
- The use and limitations of sample types to analyse tumour DNA/RNA
- Testing pathways – targeted vs panel
- Local SOPs
- Health and safety
- Consent process for minors
- Onward referrals
- Somatic and germline variants in cancer development
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 |
Outcome
Apply appropriate sample selection criteria for the commonly referred cancer samples, taking into account the implications of the referral with respect to sample type, sampling mixed cell populations, limits of detection, sensitivity of assay and patient management. |
| # 2 |
Outcome
Select the laboratory testing strategy for the commonly referred cancer samples at all stages of the patient pathway. |