Competency information
Details
Take a protein sequence and use standard bioinformatic tools to locate within a genome, annotate and infer function.
Considerations
- Theoretical basis of function prediction in bioinformatics.
- Tools for protein function prediction based on sequence similarity.
- Tools for protein function prediction based on conserved motifs and patterns.
- The use of gene ontology to annotate function.
- The use of literature resources to support function prediction.
- The processes of combining predictive tools to provide evidenced protein function.
- Best practice guidelines and quality assurance (QA; both internal and external).
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 1 | Outcome Perform analysis on DNA data and protein sequence data to infer function. |
| # 2 | Outcome Perform sequence alignment tasks followed by clustering and phylogeny. |