Competency information
Details
Observe and assist with the range of laboratory methods and their application to generate genetic test results for cancer patients
Considerations
- Principles and applications of relevant methods and techniques
- The principles of PCR and sequence methods, including the significance of contamination, sensitivity and associated hazards and risks
- The principles of chromosomal microarray and other copy number analysis techniques, including the significance of contamination, sensitivity and associated hazards and risks
- Relevant internal quality control procedures and characteristics of substandard reactions
- Factors affecting the integrity of samples and reagents and relevant sensitivities to conditions of cold, heat and light
- Principles of electrophoresis of nucleic acids
- Principles of radioactive and fluorescent image detection
- Principles of mutation detection and DNA/RNA sequencing
- Limitations and sensitivity of each test method
- The nature and effect of possible artefacts
Relevant learning outcomes
| # | Outcome |
|---|---|
| # 4 | Outcome Recognise normal cellular morphology of representative tissues and organs and common pathobiological processes associated with them |
| # 5 | Outcome Perform a range of laboratory techniques used in screening and investigating histopathological and haematological malignancy disorders |
| # 6 | Outcome Apply the principles of internal quality control and external quality assessment and draw conclusions about assay performance |
| # | Outcome |