Competency: 6

Details

Interpret and report on a range of genetic testing in haematological malignancy, including both diagnostic and follow-up (monitoring) analysis.

Considerations

• Interpretation of results including diagnostic and treatment recommendations, taking into account the relationships between chromosome abnormalities/genetic markers, other testing modalities and clinical diagnosis
• Use and critical appraisal of relevant literature and online databases.
• Role of multidisciplinary team (MDT) meetings and guidelines such as Improving Outcomes Guidance and NICE Guidelines
• The role of large scale national and international projects focussed on acquired disease. 
• Recognising that all tests have been completed to a satisfactory standard for the referral reason.  
• All information has been validated as correct. 
• Selection of correct report template for referral reason. 
• Recommendations for further referral (e.g. clinical genetics). Identify the requirements for any follow up testing, the testing methods available and the appropriate choice of test. Describe any limitations.
• Use of correct scientific and clinical terminology
• Use of relevant databases and literature in the interpretation of results.
• Communication of complex scientific information to clinicians and patients.
• Best practice guidelines compared with laboratory practice and any differences between the two
• How to identify pertinent EQA schemes; their role and practice, how these are incorporated into laboratory practice and ISO standards for lab participation in EQA schemes.

Relevant learning outcomes