Competency information

Details

Perform analyses and interpret genomic results from non-invasive liquid biopsy samples

Considerations

  • Sample suitability
  • Extraction methodologies for circulating free tumour DNA from liquid biopsies
  • Principles of the technique, including limitations and sensitivity. Internal and external quality control.
  • The quality parameters for the test.
  • Use of suitable analysis software and bioinformatics tools. How to recognise samples that require repeat testing or that have failed testing.
  • Accurate recording of results of analysis following local laboratory protocols.

Relevant learning outcomes

# Outcome
# 5 Outcome Apply the appropriate genomic testing strategy set in the context of the patient treatment pathway.
# 6 Outcome Appreciate the role of ctDNA in diagnosis and monitoring of disease