Competency information

Details

Prepare a range of diagnostic clinical reports for a lung cancer patient.

Considerations

  • How to recognise all tests have been completed to a satisfactory standard for the referral reason.
  • All information has been validated as correct. Selection of correct report template for referral reason.
  • Recommendations for further referral (e.g. clinical genetics). Identify the requirements for any follow up testing, the testing methods available and the appropriate choice of test. Describe any limitations.
  • Use of correct scientific terminology and nomenclature (e.g. HGVS).
  • Communication of complex scientific information to clinicians and patients.
  • Recommendation of suitable potential therapeutics including personalized medicine e.g. Monoclonal Antibody therapy, Tyrosine kinase inhibitor therapy (primary and secondary), Clinical trials, NICE and Cancer Drug Fund
  • The importance of sensitising and resistant mutation
  • Best practice guidelines compared with laboratory practice and any differences between the two.
  • How to identify pertinent EQA schemes; their role and practice; how these are incorporated into laboratory practice; ISO standards for lab participation in EQA schemes.
  • The calculation of residual probability following molecular testing where appropriate.
  • Use of relevant databases and the literature in the interpretation of results.
  • Pathways for obtaining further suitable samples

Relevant learning outcomes

# Outcome
# 6 Outcome Appreciate the role of ctDNA in diagnosis and monitoring of disease
# 7 Outcome Interpret and report on the relevant laboratory procedures for the diagnosis and monitoring of the patient.
# 8 Outcome Understand the assignment of risks and likelihoods based on the results of tumour analysis and the response to chemotherapy.