Title Bleeding disorders haemophilia A and haemophilia B
Type Stage Two
Code HLS155
Requirement Compulsory

Module objective

By the end of the training period trainees will, in respect of bleeding disorders – haemophilia A and haemophilia B, be able to:

  • analyse, synthesise, evaluate and apply knowledge
  • perform, adapt and master a range of technical and clinical skills and procedures
  • demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:

  • pathogenesis, severity and symptoms
  • synthesis, structure and function of FVIII and FIX
  • genetics and inheritance
  • laboratory and clinical phenotypic diagnosis and classification
  • genetic carrier and prenatal diagnosis
  • clinical aspects and presentation
  • acquired haemophilia
  • clinical aspects: symptoms, treatment principles and measures
  • clotting factor replacement therapy and prophylaxis, DDAVP, cryoprecipitate, FFP, FEIBA rVIIa, tranexamic acid
  • treatment complications: inhibitors, HIV, hepatitis, parvovirus, vCJD, thrombosis
  • ethical aspects: informed consent, genetic testing in children, Human Tissue Act.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:

  • knowledge and understanding of pathogenesis, genetics and clinical and laboratory aspects of inherited and acquired haemophilia
  • understanding of clinical management of inherited bleeding disorders
  • knowledge and understanding of ethical aspects of diagnosis in inherited haematological disorders.

Attitudes and behaviours

This module has no attitude and behaviours information.


Code Title Action
HLS1-2-1-20 Haematology (Haemostasis and Thrombosis) [v1] View