Title Anticoagulant therapy and prophylaxis
Type Stage Two
Code HLS159
Requirement Compulsory

Module objective

By the end of the training period trainees will, in respect of anticoagulant therapy and prophylaxis, be able to:

  • analyse, synthesise, evaluate and apply knowledge
  • perform, adapt and master a range of technical and clinical skills and procedures
  • demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to

  • clinical pharmacology of anticoagulant drugs
  • clinical indications of anticoagulant therapy and prophylaxis
  • laboratory monitoring of oral anticoagulants, calibration of thromboplastins, choice of thromboplastin, determination of INR, therapeutic range, complications of anticoagulant therapy, reversal of over- anticoagulation and bleeding
  • laboratory monitoring of heparin therapy (APTT, anti-Xa assay, protamine neutralisation test, near- patient monitoring), unfractionated heparin and low molecular weight heparin
  • Hirudin
  • “new anticoagulants”
  • thrombolytic therapy and laboratory control
  • antiplatelet therapy
  • issues of anticoagulant therapy and prophylaxis in thrombophilia including prophylaxis in asymptomatic thrombophilia carriers, intensity of anticoagulant therapy, and duration of anticoagulant therapy.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:

  • have knowledge and understanding of modes of action of anticoagulant drugs and their use in haematological practice
  • apply laboratory methods for anticoagulant monitoring and control
  • have knowledge and critical understanding of topical issues of anticoagulant therapy.

Attitudes and behaviours

This module has no attitude and behaviours information.


Code Title Action
HLS1-2-1-20 Haematology (Haemostasis and Thrombosis) [v1] View