Title Molecular diagnostics-Haemato-oncology
Type Stage Two
Code HLS176
Requirement Compulsory

Module objective

By the end of the training period trainees will, in respect of molecular diagnostics, be able to:

  • analyse, synthesise, evaluate and apply knowledge
  • perform, adapt and master a range of technical and clinical skills and procedures
  • demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.

Knowledge and understanding

By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to the

  • understand DNA structure and gene expression, organisation of the human genome, inheritance, mutation mechanisms
  • understand methodology, principles and practice, assay design and trouble-shooting for PCR, linkage analysis, mutation screening, DNA sequencing
  • understand of the genetic abnormalities associated with clonal proliferation in malignant haematological disease and the role, application and clinical interpretation of molecular genetics for diagnosis, prognosis and monitoring following therapy.

Technical and clinical skills

By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:

  • have a core knowledge and understanding of human molecular genetics
  • have knowledge of technical and practical aspects of molecular biology methods for the investigation of haematological malignancy
  • demonstrate appropriate use of molecular biology investigations to establish diagnosis and to produce a fully interpretative clinical diagnostic laboratory report.

Attitudes and behaviours

This module has no attitude and behaviours information.


Code Title Action
HLS1-2-2-20 Haematology (Haemato-Oncology) [v1] View