|Title||Anti viral susceptibility|
By the end of the training period trainees will, in respect of anti-viral susceptibility understanding antivirals, their mechanisms of action, clinical applications, development of and testing for resistance, be able to:
- analyse, synthesise, evaluate and apply knowledge
- perform, adapt and master a range of technical and clinical skills and procedures and
- demonstrate the attitudes and behaviours necessary for professional practice as a consultant clinical scientist dealing with the complexities, uncertainties and tensions of professional practice at this level.
Knowledge and understanding
By the end of the training period the trainee will be able to demonstrate the ability to analyse, evaluate and synthesise relevant knowledge and its application to their professional practice in relation to:
- phenotypic versus genotypic testing
- laboratory protocols, assay design, and choice of controls; limitations of assays should also be appreciated
- relevant pharmacology; include knowledge of mechanisms of action, pharmacokinetics, interactions, toxicities
- the processes for evaluation of new compounds
- phase 1, 2 and 3 clinical trials. Maintain awareness of new compounds
- the impact of antivirals on epidemiology of viral infections
- viral dynamics and the spread of resistance within the population
- how a reference laboratory works.
Technical and clinical skills
By the end of the training period the trainee will be able to demonstrate a critical understanding of current relevant research, theory and knowledge and its application to the performance, adaptation and mastery of the following technical procedures and laboratory skills:
- interpret resistance data and provide appropriate clinical advice
- be able to manipulate and interpret genotypic data and compare it against sequences stored in databases
- write clinical protocols for antiviral use.
By the end of the training period the trainee will be able to apply knowledge of anti-viral susceptibility to perform, adapt and master the clinical skills necessary to manage to:
- recognise when patients may have a virus infection which is resistant to antiviral treatment.
Attitudes and behaviours
This module has no attitude and behaviours information.